USP7 deubiquitinates and stabilizes EZH2 in prostate cancer cells

Abstract Regulation of target proteins by the ubiquitin-proteasome system (UPS) is common in a wide range of cellular events, including transcriptional regulation, cell cycle progression, differentiation, and tumorigenesis. Ubiquitin-specific protease 7 (USP7) has been implicated in tumor developmen...

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Bibliographic Details
Main Authors: Jae Eun Lee, Chan Mi Park, Jung Hwa Kim
Format: Article
Language:English
Published: Sociedade Brasileira de Genética 2020-05-01
Series:Genetics and Molecular Biology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572020000400706&tlng=en