Inorganic Phosphate-Induced Extracellular Vesicles from Vascular Smooth Muscle Cells Contain Elevated Levels of Hyaluronic Acid, Which Enhance Their Interaction with Very Small Superparamagnetic Iron Oxide Particles

Inorganic Phosphate-Induced Extracellular Vesicles from Vascular Smooth Muscle Cells Contain Elevated Levels of Hyaluronic Acid, Which Enhance Their Interaction with Very Small Superparamagnetic Iron Oxide Particles

Patients with chronic kidney disease (CKD) have a high prevalence of hyperphosphatemia, where uremic toxins like inorganic phosphate (Pi) induce a cardiovascular remodeling. Related disorders like atherosclerosis bear the risk of increased morbidity and mortality. We previously found that Pi stimula...

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Bibliographic Details
Main Authors: Christian Freise, Karina Biskup, Véronique Blanchard, Jörg Schnorr, Matthias Taupitz
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:International Journal of Molecular Sciences
Subjects:
extracellular vesicles
inorganic phosphate
uremic toxins
VSOP
hyaluronic acid
glycosaminoglycans
Online Access:https://www.mdpi.com/1422-0067/25/5/2571

Internet

https://www.mdpi.com/1422-0067/25/5/2571

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