The role of autophagy in SIM mediated anti‐inflammatory osteoclastogenesis through NLRP3 signaling pathway

The role of autophagy in SIM mediated anti‐inflammatory osteoclastogenesis through NLRP3 signaling pathway

Abstract Background Inflammatory bone resorption is a prominent risk factor for implantation failure. Simvastatin (SIM) has anti‐inflammatory effects independent of cholesterol lowering and reduces osteoclastogenesis by decreasing both the number and activity of osteoclasts. However, the specific me...

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Bibliographic Details
Main Authors: Yuting Cheng, Wenjun Jin, Lin Zheng, Xiaolin Huang, Shanshan Luo, Wei Hong, Jian Liao, Bancha Samruajbenjakun, Chidchanok Leethanakul
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Immunity, Inflammation and Disease
Subjects:
autophagy
inflammatory bone resorption
NLRP3
osteoclast
Simvastatin
Online Access:https://doi.org/10.1002/iid3.1145

Internet

https://doi.org/10.1002/iid3.1145

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