TLC599 in patients with osteoarthritis of the knee: a phase IIa, randomized, placebo-controlled, dose-finding study

Abstract Background Corticosteroid injection for knee osteoarthritis is limited by its modest duration of treatment effect. The liposome formulation of dexamethasone sodium phosphate (TLC599) was developed for the sustained relief of osteoarthritis pain. This clinical study was conducted to evaluate...

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Bibliographic Details
Main Authors: David J. Hunter, Chi-Ching Chang, James Cheng-Chung Wei, Hsiao-Yi Lin, Carl Brown, Tien-Tzu Tai, Chih-Feng Wu, Wing Chia-Ming Chuang, Sheue-Fang Shih
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Arthritis Research & Therapy
Subjects:
Online Access:https://doi.org/10.1186/s13075-022-02739-4