Mice Deficient in Cyp4a14 Have An Increased Number of Goblet Cells and Attenuated Dextran Sulfate Sodium-Induced Colitis

Mice Deficient in Cyp4a14 Have An Increased Number of Goblet Cells and Attenuated Dextran Sulfate Sodium-Induced Colitis

Background/Aims: Cyp4a14 is a member of cytochrome P450 (Cyp450) enzyme superfamily that possesses NADPH monooxygenase activity, which catalyzes omega-hydroxylation of medium-chain fatty acids and arachidonic acid. Study suggests that down-regulation of Cyp4a14 has an anti-inflammatory response in i...

Full description

Bibliographic Details
Main Authors: Qingxia Xuan, Yunfeng Zhou, Binbin Tan, Zhongyue Xiao, Shizhen Dong, Faliang Dai, Lei Gao, Tengfei Guo, Pan Chen, Jie Sun, Dandan Feng, Jianjun Jin, Fong-Fong Chu, Qiang Gao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Colitis
Cyp4a14
Goblet cells
NADPH oxidase
Online Access:https://www.karger.com/Article/FullText/495087

Internet

https://www.karger.com/Article/FullText/495087

Similar Items