Characterization of Affective Behaviors and Motor Functions in Mice With a Striatal-Specific Deletion of Bmal1 and Per2

Characterization of Affective Behaviors and Motor Functions in Mice With a Striatal-Specific Deletion of Bmal1 and Per2

The expression of circadian clock genes, either centrally or in the periphery, has been shown to play an integral role in the control of behavior. Brain region-specific downregulation of clock genes revealed behavioral phenotypes associated with neuropsychiatric disorders and neurodegenerative disea...

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Bibliographic Details
Main Authors: Konrad Schoettner, Mariana Alonso, Margo Button, Cassandra Goldfarb, Juliana Herrera, Nour Quteishat, Christiane Meyer, Andreas Bergdahl, Shimon Amir
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Physiology
Subjects:
clock genes
medium spiny neurons
mood-and anxiety-like behavior
motor coordination
mitochondrial respiration
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.922080/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.922080/full

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