Peptide density targets and impedes triple negative breast cancer metastasis
The C-X-C chemokine receptor type 4 (CXCR4) pathway is a key regulator of cancer metastasis. Here, the authors present a method to block CXCR4 and thereby inhibit breast cancer metastasis by developing a liposome that presents CXCR4-binding peptides in a multivalent fashion.
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2018-07-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05035-5 |