In Vivo and In Vitro Characterization of the Recently Emergent PRRSV 1-4-4 L1C Variant (L1C.5) in Comparison with Other PRRSV-2 Lineage 1 Isolates

The recently emerged PRRSV 1-4-4 L1C variant (L1C.5) was in vivo and in vitro characterized in this study in comparison with three other contemporary 1-4-4 isolates (L1C.1, L1A, and L1H) and one 1-7-4 L1A isolate. Seventy-two 3-week-old PRRSV-naive pigs were divided into six groups with twelve pigs/...

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Main Authors: Gaurav Rawal, Marcelo N. Almeida, Phillip C. Gauger, Jeffrey J. Zimmerman, Fangshu Ye, Christopher J. Rademacher, Betsy Armenta Leyva, Berenice Munguia-Ramirez, Grzegorz Tarasiuk, Loni L. Schumacher, Ethan K. Aljets, Joseph T. Thomas, Jin-Hui Zhu, Jolie B. Trexel, Jianqiang Zhang
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Viruses
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Online Access:https://www.mdpi.com/1999-4915/15/11/2233