The Role of NOX4 and TRX2 in Angiogenesis and Their Potential Cross-Talk
The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) family is the major source of reactive oxygen species (ROS) in the vascular system. In this family, NOX4, a constitutive active form of NOXs, plays an important role in angiogenesis. Thioredoxin 2 (TRX2) is a key mitochondrial red...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2017-06-01
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Series: | Antioxidants |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3921/6/2/42 |