The Role of NOX4 and TRX2 in Angiogenesis and Their Potential Cross-Talk

The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) family is the major source of reactive oxygen species (ROS) in the vascular system. In this family, NOX4, a constitutive active form of NOXs, plays an important role in angiogenesis. Thioredoxin 2 (TRX2) is a key mitochondrial red...

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Bibliographic Details
Main Authors: Chaofei Chen, Li Li, Huanjiao Jenny Zhou, Wang Min
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Antioxidants
Subjects:
Online Access:http://www.mdpi.com/2076-3921/6/2/42