Improving ancient DNA genome assembly

Most reconstruction methods for genomes of ancient origin that are used today require a closely related reference. In order to identify genomic rearrangements or the deletion of whole genes, de novo assembly has to be used. However, because of inherent problems with ancient DNA, its de novo assembly...

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Bibliographic Details
Main Authors: Alexander Seitz, Kay Nieselt
Format: Article
Language:English
Published: PeerJ Inc. 2017-04-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/3126.pdf