Identification of Trim24 as a new NTRK3 fusion partner in lung adenocarcinoma: Diagnostic challenges of a novel fusion

Identification of Trim24 as a new NTRK3 fusion partner in lung adenocarcinoma: Diagnostic challenges of a novel fusion

Reliable neurotrophin kinase (NTRK) fusion assessment is of special relevance since durable responses to targeted therapies have been observed regardless tumor type, NTRK gene or fusion partner. The most prevalent NTRK fusion in solid tumors is the ETV6-NTRK3, although alternative NTRK3 translocatio...

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Bibliographic Details
Main Authors: Almudena Santón, Eugenia Olmedo, Tamara Caniego-Casas, Amparo Benito, Mónica García-Cosío, Jorge Esteban-Villarrubia, Pilar Garrido, José Palacios
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Human Pathology Reports
Subjects:
NTRK3 fusions
Non-small-cell lung cancer
RNA-NGS
Targeted-therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2772736X22000378

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http://www.sciencedirect.com/science/article/pii/S2772736X22000378

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