PIWI silencing mechanism involving the retrotransposon nimbus orchestrates resistance to infection with Schistosoma mansoni in the snail vector, Biomphalaria glabrata.

<h4>Background</h4>Schistosomiasis remains widespread in many regions despite efforts at its elimination. By examining changes in the transcriptome at the host-pathogen interface in the snail Biomphalaria glabrata and the blood fluke Schistosoma mansoni, we previously demonstrated that a...

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Bibliographic Details
Main Authors: Michael Smith, Swara Yadav, Olayemi G Fagunloye, Nana Adjoa Pels, Daniel A Horton, Nashwah Alsultan, Andrea Borns, Carolyn Cousin, Freddie Dixon, Victoria H Mann, Clarence Lee, Paul J Brindley, Najib M El-Sayed, Joanna M Bridger, Matty Knight
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0009094