Chick Chorioallantoic Membrane as a Patient-Derived Xenograft Model for Uveal Melanoma: Imaging Modalities for Growth and Vascular Evaluation

Chick Chorioallantoic Membrane as a Patient-Derived Xenograft Model for Uveal Melanoma: Imaging Modalities for Growth and Vascular Evaluation

Background: Patient-derived tumor xenografts (PDXs) have emerged as valuable preclinical in vivo models in oncology as they largely retain the polygenomic architecture of the human tumors from which they originate. Although animal models are accompanied by cost and time constraints and a low engraft...

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Bibliographic Details
Main Authors: Theodora Tsimpaki, Nikolaos E. Bechrakis, Berthold Seitz, Miriam M. Kraemer, Hongtao Liu, Sami Dalbah, Ekaterina Sokolenko, Utta Berchner-Pfannschmidt, Miltiadis Fiorentzis
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Cancers
Subjects:
uveal melanoma
patient-derived xenograft
CAM assay
in vivo human uveal melanoma model
real-time imaging
OCT
Online Access:https://www.mdpi.com/2072-6694/15/5/1436

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https://www.mdpi.com/2072-6694/15/5/1436

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