RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect

RXR Agonists Enhance Lenalidomide Anti-Myeloma Activity and T Cell Functions while Retaining Glucose-Lowering Effect

Retinoid X receptor (<i>RXR</i>) heterodimerizes with the <i>PPAR</i> nuclear hormone receptor and regulates its downstream events. We investigated the effects of <i>RXR</i> agonists (LG100754, bexarotene, AGN194204, and LG101506) on lenalidomide’s anti-myeloma ac...

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Bibliographic Details
Main Authors: Jian Wu, Xiaobei Wang, Min Zhang, Parker Mathews, Yubin Kang
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Cells
Subjects:
immunomodulatory drugs
<i>PPAR</i>
diabetes
dyslipidemia
CpG island
methylation
Online Access:https://www.mdpi.com/2073-4409/12/15/1993

Internet

https://www.mdpi.com/2073-4409/12/15/1993

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