Pathologic complete response to neoadjuvant imatinib of a gastric stromal tumor with concomitant mutations in KIT: A case report and literature review

Pathologic complete response to neoadjuvant imatinib of a gastric stromal tumor with concomitant mutations in KIT: A case report and literature review

Key clinical message We report the first case of pathologic complete response (pCR) to neoadjuvant imatinib in a gastric stromal tumor harboring KIT mutations in both exons 11 and 9. The significance of this co‐occurrence is unknown and might increase the responsiveness of gastrointestinal stromal t...

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Bibliographic Details
Main Authors: Mariem Ben Rekaya, Feryel Ksontini, Linda Bel Haj Kacem, Farah Sassi, Emna Harigua‐Souiai, Ryma Boujneh, Ahmed H'mayada, Yosra Zaimi, Mouna Ayadi, Mediha Trabelsi, Ridha Mrad, Soumaya Rammeh
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:Clinical Case Reports
Subjects:
imatinib
KIT
mutation
pathologic complete response
PDGFRA
Online Access:https://doi.org/10.1002/ccr3.7463

Internet

https://doi.org/10.1002/ccr3.7463

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