Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content
<p>Abstract</p> <p>Background</p> <p>Human polyomavirus JC (JCV) is the etiologic agent of a brain disease, known as progressive multifocal leukoencephalopathy (PML). The JCV genome encodes a small multifunctional phospho-protein, agnoprotein, from the late coding regio...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-05-01
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Series: | Virology Journal |
Subjects: | |
Online Access: | http://www.virologyj.com/content/8/1/255 |