Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content

Infection by agnoprotein-negative mutants of polyomavirus JC and SV40 results in the release of virions that are mostly deficient in DNA content

<p>Abstract</p> <p>Background</p> <p>Human polyomavirus JC (JCV) is the etiologic agent of a brain disease, known as progressive multifocal leukoencephalopathy (PML). The JCV genome encodes a small multifunctional phospho-protein, agnoprotein, from the late coding regio...

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Bibliographic Details
Main Authors: Safak Mahmut, White Martyn K, Saribas Abdullah S, Sariyer Ilker K
Format: Article
Language:English
Published: BMC 2011-05-01
Series:Virology Journal
Subjects:
JC virus
BK virus
SV40
replication
transcription
virion release
Online Access:http://www.virologyj.com/content/8/1/255

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