The Therapeutic and Diagnostic Potential of Phospholipase C Zeta, Oocyte Activation, and Calcium in Treating Human Infertility

The Therapeutic and Diagnostic Potential of Phospholipase C Zeta, Oocyte Activation, and Calcium in Treating Human Infertility

Oocyte activation, a fundamental event during mammalian fertilisation, is initiated by concerted intracellular patterns of calcium (Ca<sup>2+</sup>) release, termed Ca<sup>2+</sup> oscillations, predominantly driven by testis-specific phospholipase C zeta (PLCζ). Ca<sup>...

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Bibliographic Details
Main Authors: Haia M. R. Abdulsamad, Zoha F. Murtaza, Hessa M. AlMuhairi, Wjdan S. Bafleh, Salma A. AlMansoori, Shaikha A. AlQubaisi, Hamdan Hamdan, Junaid Kashir
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Pharmaceuticals
Subjects:
phospholipase C zeta (PLCzeta)
oocyte activation
male infertility
sperm
fertilisation
calcium
Online Access:https://www.mdpi.com/1424-8247/16/3/441

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https://www.mdpi.com/1424-8247/16/3/441

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