Mass spectrometry-based absolute quantification of amyloid proteins in pathology tissue specimens: Merits and limitations.

Mass spectrometry-based absolute quantification of amyloid proteins in pathology tissue specimens: Merits and limitations.

To clarify the significance of quantitative analyses of amyloid proteins in clinical practice and in research relating to systemic amyloidoses, we applied mass spectrometry-based quantification by isotope-labeled cell-free products (MS-QBIC) to formalin-fixed, paraffin-embedded (FFPE) tissues. The t...

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Bibliographic Details
Main Authors: Makiko Ogawa, Yukako Shintani-Domoto, Yoshiki Nagashima, Koji L Ode, Aya Sato, Yoshihiro Shimizu, Kenichi Ohashi, Michael H A Roehrl, Tetsuo Ushiku, Hiroki R Ueda, Masashi Fukayama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0235143

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https://doi.org/10.1371/journal.pone.0235143

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