Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Prophylaxis Trials: A Patient-Level Pooled Analysis

Modeling the Probability of HIV Infection over Time in High-Risk Seronegative Participants Receiving Placebo in Five Randomized Double-Blind Placebo-Controlled HIV Pre-Exposure Prophylaxis Trials: A Patient-Level Pooled Analysis

The World Health Organization recommends pre-exposure prophylaxis (PrEP) for individuals at substantial risk of HIV infection. The aim of this analysis is to quantify the individual risk of HIV infection over time, using a large database of high-risk individuals (<i>n</i> = 5583). We use...

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Bibliographic Details
Main Authors: Maria Garcia-Cremades, Craig W. Hendrix, Priya Jayachandran, Natasha Strydom, Leah Jarlsberg, Robert Grant, Connie L. Celum, Michael Martin, Jared M. Baeten, Jeanne Marrazzo, Peter Anderson, Kachit Choopanya, Suphak Vanichseni, David V. Glidden, Radojka M. Savic
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceutics
Subjects:
HIV prevention trials
key and vulnerable populations
risk factors
risk phenotypes
modeling
Online Access:https://www.mdpi.com/1999-4923/14/9/1801

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https://www.mdpi.com/1999-4923/14/9/1801

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