Impaired Response to Mismatch Novelty in the Li<sup>2+</sup>-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic Inputs

Impaired Response to Mismatch Novelty in the Li<sup>2+</sup>-Pilocarpine Rat Model of TLE: Correlation with Hippocampal Monoaminergic Inputs

Novelty detection, crucial to episodic memory formation, is impaired in epileptic patients with mesial temporal lobe resection. Mismatch novelty detection, that activates the hippocampal CA1 area in humans and is vital for memory reformulation and reconsolidation, is also impaired in patients with h...

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Bibliographic Details
Main Authors: Carlos Nascimento, Vasco Guerreiro-Pinto, Seweryn Pawlak, Ana Caulino-Rocha, Laia Amat-Garcia, Diana Cunha-Reis
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Biomedicines
Subjects:
mismatch novelty
epilepsy
learning and memory
hippocampus
5-HT
catecholamines
Online Access:https://www.mdpi.com/2227-9059/12/3/631

Internet

https://www.mdpi.com/2227-9059/12/3/631

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