Activating the DNA Damage Response and Suppressing Innate Immunity: Human Papillomaviruses Walk the Line

Activation of the DNA damage response (DDR) by external agents can result in DNA fragments entering the cytoplasm and activating innate immune signaling pathways, including the stimulator of interferon genes (STING) pathway. The consequences of this activation can result in alterations in the cell c...

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Bibliographic Details
Main Authors: Claire D. James, Dipon Das, Molly L. Bristol, Iain M. Morgan
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/9/6/467