B-cell immune dysregulation with low soluble CD22 levels in refractory seronegative myasthenia gravis

Myasthenia gravis (MG), primarily caused by acetylcholine receptor (AChR) autoantibodies, is a chronic autoimmune disorder causing severe muscle weakness and fatigability. In particular, seronegative MG constitutes 10%–15% of MG cases and presents diagnostic challenges especially in early-onset fema...

Full description

Bibliographic Details
Main Authors: Yuumi Okuzono, Shuuichi Miyakawa, Tatsuo Itou, Masaki Sagara, Masashi Iwata, Kei Ishizuchi, Koji Sekiguchi, Haruhiko Motegi, Munenori Oyama, Dnyaneshwar Warude, Yusuke Kikukawa, Shigeaki Suzuki
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1382320/full