Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement

Baicalein Attenuates Pyroptosis and Endoplasmic Reticulum Stress Following Spinal Cord Ischemia-Reperfusion Injury via Autophagy Enhancement

BackgroundSpinal cord ischemia-reperfusion injury (SCIRI) is the main complication after the repair of a complex thoracoabdominal aortic aneurysm. Many clinical treatments are not ideal due to the complex pathophysiological process of this injury. Baicalein (BA), a component derived from the roots o...

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Bibliographic Details
Main Authors: Chenyu Wu, Hui Xu, Jiafeng Li, Xinli Hu, Xingyu Wang, Yijia Huang, Yao Li, Sunren Sheng, Yongli Wang, Huazi Xu, Wenfei Ni, Kailiang Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Pharmacology
Subjects:
baicalein
spinal cord ischemia-reperfusion injury
autophagy
pyroptosis
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.01076/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.01076/full

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