Wnt Lipidation and Modifiers in Intestinal Carcinogenesis and Cancer

The wingless (Wnt) signaling is suggested as a fundamental hierarchical pathway in regulation of proliferation and differentiation of cells. The Wnt ligands are small proteins of about 40 kDa essentially for regulation and initiation of the Wnt activity. They are secreted proteins requiring acylatio...

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Bibliographic Details
Main Authors: Elke Kaemmerer, Nikolaus Gassler
Format: Article
Language:English
Published: MDPI AG 2016-07-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/7/69