Scaffold-Based (Matrigel™) 3D Culture Technique of Glioblastoma Recovers a Patient-like Immunosuppressive Phenotype

Scaffold-Based (Matrigel™) 3D Culture Technique of Glioblastoma Recovers a Patient-like Immunosuppressive Phenotype

Conventional 2D cultures are commonly used in cancer research though they come with limitations such as the lack of microenvironment or reduced cell heterogeneity. In this study, we investigated in what respect a scaffold-based (Matrigel™) 3D culture technique can ameliorate the limitations of 2D cu...

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Bibliographic Details
Main Authors: Frank K. Braun, Tanja Rothhammer-Hampl, Julia Lorenz, Sandra Pohl, Ayse-Nur Menevse, Arabel Vollmann-Zwerenz, Elisabeth Bumes, Maren Büttner, Saida Zoubaa, Martin Proescholdt, Nils O. Schmidt, Peter Hau, Philipp Beckhove, Beate Winner, Markus J. Riemenschneider
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
brain cancer
tumor organoids
GBM
next-generation sequencing
single-cell RNA sequencing
Online Access:https://www.mdpi.com/2073-4409/12/14/1856

Internet

https://www.mdpi.com/2073-4409/12/14/1856

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