IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection

IL-17 signalling is critical for controlling subcutaneous adipose tissue dynamics and parasite burden during chronic murine Trypanosoma brucei infection

Abstract In the skin, Trypanosoma brucei colonises the subcutaneous white adipose tissue, and is proposed to be competent for forward transmission. The interaction between parasites, adipose tissue, and the local immune system is likely to drive the adipose tissue wasting and weight loss observed in...

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Bibliographic Details
Main Authors: Matthew C. Sinton, Praveena R. G. Chandrasegaran, Paul Capewell, Anneli Cooper, Alex Girard, John Ogunsola, Georgia Perona-Wright, Dieudonné M Ngoyi, Nono Kuispond, Bruno Bucheton, Mamadou Camara, Shingo Kajimura, Cécile Bénézech, Neil A. Mabbott, Annette MacLeod, Juan F. Quintana
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-42918-8

Internet

https://doi.org/10.1038/s41467-023-42918-8

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