Structure-function analysis of two variants of mumps virus hemagglutinin-neuraminidase protein

Structure-function analysis of two variants of mumps virus hemagglutinin-neuraminidase protein

A point mutation from guanine (G) to adenine (A) at nucleotide position 1081 in the hemagglutinin-neuraminidase (HN) gene has been associated with neurovirulence of Urabe AM9 mumps virus vaccine. This mutation corresponds to a glutamic acid (E) to lysine (K) change at position 335 in the HN glycopro...

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Bibliographic Details
Main Authors: Gerardo Santos-López, Thomas Scior, María del Tránsito Borraz-Argüello, Verónica Vallejo-Ruiz, Irma Herrera-Camacho, José Tapia-Ramírez, Julio Reyes-Leyva
Format: Article
Language:English
Published: Elsevier
Series:Brazilian Journal of Infectious Diseases
Subjects:
Hemagglutinin-neuraminidasa
mumps virus
paramyxovirus
3D structure prediction
sialic acid
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000100007&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1413-86702009000100007&lng=en&tlng=en

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