TMEM44-AS1 promotes esophageal squamous cell carcinoma progression by regulating the IGF2BP2-GPX4 axis in modulating ferroptosis

Abstract The long non-coding RNA (lncRNA) TMEM44-AS1 is a novel lncRNA whose pro-carcinogenic role in gastric cancer and glioma has been demonstrated. However, its function in esophageal squamous cell carcinoma (ESCC) is unknown. In this study, we identified that TMEM44-AS1 was highly expressed in E...

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Bibliographic Details
Main Authors: Ruotong Yang, Junhu Wan, Liwei Ma, Fuyou Zhou, Zhengwu Yang, Zhuofang Li, Mingyuan Zhang, Liang Ming
Format: Article
Language:English
Published: Nature Publishing Group 2023-12-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01727-0