m6A methylation modification and immune cell infiltration: implications for targeting the catalytic subunit m6A-METTL complex in gastrointestinal cancer immunotherapy

m6A methylation modification and immune cell infiltration: implications for targeting the catalytic subunit m6A-METTL complex in gastrointestinal cancer immunotherapy

N6-methyladenosine (m6A) methylation modification is a ubiquitous RNA modification involved in the regulation of various cellular processes, including regulation of RNA stability, metabolism, splicing and translation. Gastrointestinal (GI) cancers are some of the world’s most common and fatal cancer...

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Bibliographic Details
Main Authors: Chen Peng, Fen Xiong, Xi Pu, Zhangmin Hu, Yufei Yang, Xuehan Qiao, Yuchun Jiang, Miao Han, Deqiang Wang, Xiaoqin Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Immunology
Subjects:
N 6 -methyladenosine (m 6 A) methylation modification
catalytic subunit m 6 A-METTL complex
METTL3/14
immune cell infiltration
immunotherapy
gastrointestinal cancers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1326031/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1326031/full

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