Central Nervous System Stimulants Limit Caffeine Transport at the Blood–Cerebrospinal Fluid Barrier

Central Nervous System Stimulants Limit Caffeine Transport at the Blood–Cerebrospinal Fluid Barrier

Caffeine, a common ingredient in energy drinks, crosses the blood–brain barrier easily, but the kinetics of caffeine across the blood–cerebrospinal fluid barrier (BCSFB) has not been investigated. Therefore, 127 autopsy cases (Group A, 30 patients, stimulant-detected group; and Group B, 97 patients,...

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Bibliographic Details
Main Authors: Kei Ikeda-Murakami, Naoto Tani, Tomoya Ikeda, Yayoi Aoki, Takaki Ishikawa
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
caffeine
stimulants
blood–cerebrospinal fluid barrier (BCSFB)
BCSFB model
choroid plexus
vacuolation
Online Access:https://www.mdpi.com/1422-0067/23/3/1862

Internet

https://www.mdpi.com/1422-0067/23/3/1862

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