Single-cell transcriptome analysis reveals cellular reprogramming and changes of immune cell subsets following tetramethylpyrazine treatment in LPS-induced acute lung injury

Background Acute lung injury (ALI) is a disordered pulmonary disease characterized by acute respiratory insufficiency with tachypnea, cyanosis refractory to oxygen and diffuse alveolar infiltrates. Despite increased research into ALI, current clinical treatments lack effectiveness. Tetramethylpyrazi...

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Detalhes bibliográficos
Principais autores: Mingyan Wu, Shanmei Wang, Xiaolan Chen, Li Shen, Jurong Ding, Hongbin Jiang
Formato: Artigo
Idioma:English
Publicado em: PeerJ Inc. 2025-01-01
coleção:PeerJ
Assuntos:
Acesso em linha:https://peerj.com/articles/18772.pdf