Involvement of orexin type-2 receptors in genetic absence epilepsy rats

IntroductionOrexin is a neuropeptide neurotransmitter that regulates the sleep/wake cycle produced by the lateral hypothalamus neurons. Recent studies have shown the involvement of orexin system in epilepsy. Limited data is available about the possible role of orexins in the pathophysiology of absen...

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Main Authors: Aylin Toplu, Nursima Mutlu, Elif Tuğçe Erdeve, Özge Sariyildiz, Musa Çelik, Devrim Öz-Arslan, Özlem Akman, Zoltan Molnár, Nihan Çarçak, Filiz Onat
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Neurology
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Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2023.1282494/full