The Role of Mesothelin in Activation of Portal Fibroblasts in Cholestatic Liver Injury

Fibrosis is a common consequence of abnormal wound healing, which is characterized by infiltration of myofibroblasts and formation of fibrous scar. In liver fibrosis, activated Hepatic Stellate Cells (aHSCs) and activated Portal Fibroblasts (aPFs) are the major contributors to the origin of hepatic...

Full description

Bibliographic Details
Main Authors: Takahiro Nishio, Yukinori Koyama, Hiroaki Fuji, Kei Ishizuka, Keiko Iwaisako, Kojiro Taura, Etsuro Hatano, David A. Brenner, Tatiana Kisseleva
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/11/1589