A novobiocin derivative, XN4, triggers ferroptosis in gastric cancer cells via the activation of NOX4

Context A novobiocin derivative, XN4, has been shown to promote cell apoptosis in chronic myeloid leukaemia.Objective This study explores the mechanism by which XN4 promotes ferroptosis of gastric cancer (GC) cells.Materials and methods Human GC SGC-7901 and BGC-823 cells were treated with different...

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Bibliographic Details
Main Authors: Rongrong Li, Bin Yin, Deyu Zeng, Zhenyang Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Pharmaceutical Biology
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/13880209.2022.2099431