Synaptic Plasticity on Motoneurons After Axotomy: A Necessary Change in Paradigm

Motoneurons axotomized by peripheral nerve injuries experience profound changes in their synaptic inputs that are associated with a neuroinflammatory response that includes local microglia and astrocytes. This reaction is conserved across different types of motoneurons, injuries, and species, but al...

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Bibliographic Details
Main Authors: Francisco J. Alvarez, Travis M. Rotterman, Erica T. Akhter, Alicia R. Lane, Arthur W. English, Timothy C. Cope
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2020.00068/full