Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers

Effects of renal function on pharmacokinetics and pharmacodynamics of lesinurad in adult volunteers

Michael Gillen,1 Shakti Valdez,2 Dongmei Zhou,2 Bradley Kerr,2 Caroline A Lee,2 Zancong Shen2 1AstraZeneca LP, Gaithersburg, MD, 2Ardea Biosciences, Inc., San Diego, CA, USA Introduction: Lesinurad is a selective uric acid reabsorption inhibitor approved for the treatment of gout in combination wi...

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Bibliographic Details
Main Authors: Gillen M, Valdez S, Zhou D, Kerr B, Lee CA, Shen Z
Format: Article
Language:English
Published: Dove Medical Press 2016-11-01
Series:Drug Design, Development and Therapy
Subjects:
Lesinurad
pharmacodynamics
pharmacokinetics
renal function
serum urate
Online Access:https://www.dovepress.com/effects-of-renal-function-on-pharmacokinetics-and-pharmacodynamics-of--peer-reviewed-article-DDDT

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https://www.dovepress.com/effects-of-renal-function-on-pharmacokinetics-and-pharmacodynamics-of--peer-reviewed-article-DDDT

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