A randomized controlled double-blind study of rotigotine on neuropsychiatric symptoms in de novo PD

Abstract Management of apathy, depression and anxiety in Parkinson’s disease (PD) represents a challenge. Dopamine agonists have been suggested to be effective. This multicenter, randomized (1:1), double-blind study assessed the 6-month effect of rotigotine versus placebo on apathy, depression and a...

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Bibliographic Details
Main Authors: A. Castrioto, S. Thobois, M. Anheim, J. L. Quesada, E. Lhommée, H. Klinger, A. Bichon, E. Schmitt, F. Durif, J. P. Azulay, J. L. Houeto, N. Longato, C. Philipps, P. Pelissier, E. Broussolle, E. Moro, C. Tranchant, V. Fraix, P. Krack, for the Honeymoon study group
Format: Article
Language:English
Published: Nature Portfolio 2020-12-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-020-00142-x