A randomized controlled double-blind study of rotigotine on neuropsychiatric symptoms in de novo PD
Abstract Management of apathy, depression and anxiety in Parkinson’s disease (PD) represents a challenge. Dopamine agonists have been suggested to be effective. This multicenter, randomized (1:1), double-blind study assessed the 6-month effect of rotigotine versus placebo on apathy, depression and a...
Main Authors: | A. Castrioto, S. Thobois, M. Anheim, J. L. Quesada, E. Lhommée, H. Klinger, A. Bichon, E. Schmitt, F. Durif, J. P. Azulay, J. L. Houeto, N. Longato, C. Philipps, P. Pelissier, E. Broussolle, E. Moro, C. Tranchant, V. Fraix, P. Krack, for the Honeymoon study group |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2020-12-01
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Series: | npj Parkinson's Disease |
Online Access: | https://doi.org/10.1038/s41531-020-00142-x |
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