Smoking-associated increase in mucins 1 and 4 in human airways

Abstract Rationale Smoking-related chronic obstructive pulmonary disease (COPD) is associated with dysregulated production of mucus. Mucins (MUC) are important both for mucus secretion and epithelial defense. We have examined the distribution of MUC1 and MUC4 in the airway epithelial cells of never-...

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Bibliographic Details
Main Authors: Heta Merikallio, Riitta Kaarteenaho, Sara Lindén, Médea Padra, Reza Karimi, Chuan-Xing Li, Elisa Lappi-Blanco, Åsa M. Wheelock, Magnus C. Sköld
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-020-01498-7