Inducible Bronchus-Associated Lymphoid Tissues (iBALT) Serve as Sites of B Cell Selection and Maturation Following Influenza Infection in Mice

Inducible Bronchus-Associated Lymphoid Tissues (iBALT) Serve as Sites of B Cell Selection and Maturation Following Influenza Infection in Mice

Seasonally recurrent influenza virus infections are a significant cause of global morbidity and mortality. In murine models, primary influenza infection in the respiratory tract elicits potent humoral responses concentrated in the draining mediastinal lymph node and the spleen. In addition to immuni...

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Bibliographic Details
Main Authors: Hyon-Xhi Tan, Robyn Esterbauer, Hillary A. Vanderven, Jennifer A. Juno, Stephen J. Kent, Adam K. Wheatley
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
germinal center (GC)
influenza
iBALT
B cell
humoral immunity
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00611/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.00611/full

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