Ro60 and La ribonucleoproteins become self-aggregated by cell stress

Ro is a cellular particle composed by three ribonucleoproteins of 60, 54 and 52 kDa (1-3). Ro60 forms a complex with one of the 1-5 hYRNAs (4). Antigenic properties of Ro were described by Clark in 1969 using autoimmune sera (5), and it is broadly accepted that Ro is recognized by autoantibodies fro...

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Bibliographic Details
Main Authors: E. Avalos-Díaz, D. Herrera-van-Oostdam, S.H. Sánchez-Rodríguez, R. Herrera-Esparza
Format: Article
Language:English
Published: PAGEPress Publications 2011-09-01
Series:Reumatismo
Online Access:http://www.reumatismo.org/index.php/reuma/article/view/339