Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study.

Metformin exposure, maternal PCOS status and fetal venous liver circulation: A randomized, placebo-controlled study.

<h4>Background</h4>Metformin is prescribed to women with polycystic ovary syndrome (PCOS) to prevent pregnancy complications. Children exposed to metformin vs. placebo in utero, have increased head circumference at birth and are more overweight and obese at 8 years of age. Also, maternal...

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Main Authors: Sindre Grindheim, Cathrine Ebbing, Henriette Odland Karlsen, Svein Magne Skulstad, Francisco Gómez Real, Marianne Lønnebotn, Tone Løvvik, Eszter Vanky, Jørg Kessler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0262987

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https://doi.org/10.1371/journal.pone.0262987

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