Viral-Mediated Knockdown of Nucleus Accumbens Shell PAC1 Receptor Promotes Excessive Alcohol Drinking in Alcohol-Preferring Rats

Alcohol use disorder (AUD) is a chronic, relapsing disorder whose genetic and environmental susceptibility components are not fully understood. Neuropeptidergic signaling has been repeatedly implicated in modulating excessive alcohol drinking, especially within sub-regions of the striatum. Here, we...

Full description

Bibliographic Details
Main Authors: Margaret A. Minnig, Tayun Park, Maria Echeveste Sanchez, Pietro Cottone, Valentina Sabino
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-12-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2021.787362/full