Soluble Klotho Improves Hepatic Glucose and Lipid Homeostasis in Type 2 Diabetes

Soluble Klotho Improves Hepatic Glucose and Lipid Homeostasis in Type 2 Diabetes

Type 2 diabetes (T2D) is one of the most escalating global metabolic diseases, which is highly associated with insulin resistance (IR) and risk of combination with nonalcoholic fatty liver disease (NAFLD). Previous studies suggest that soluble klotho (sKL) could serve as a circulating hormone to med...

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Bibliographic Details
Main Authors: Huiying Gu, Wei Jiang, Nan You, Xiaobing Huang, Yuming Li, Xuehui Peng, Rui Dong, Zheng Wang, Yinan Zhu, Ke Wu, Jing Li, Lu Zheng
Format: Article
Language:English
Published: Elsevier 2020-09-01
Series:Molecular Therapy: Methods & Clinical Development
Subjects:
sKL
T2D
IR
NAFLD
glucose and lipid homeostasis
PPARα
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050120301686

Internet

http://www.sciencedirect.com/science/article/pii/S2329050120301686

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