Basement membrane product, endostatin, as a link between inflammation, coagulation and vascular permeability in COVID-19 and non-COVID-19 acute respiratory distress syndrome

Basement membrane product, endostatin, as a link between inflammation, coagulation and vascular permeability in COVID-19 and non-COVID-19 acute respiratory distress syndrome

BackgroundImmune cell recruitment, endothelial cell barrier disruption, and platelet activation are hallmarks of lung injuries caused by COVID-19 or other insults which can result in acute respiratory distress syndrome (ARDS). Basement membrane (BM) disruption is commonly observed in ARDS, however,...

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Bibliographic Details
Main Authors: Katharina Jandl, Johannes Lorenz Berg, Anna Birnhuber, Elisabeth Fliesser, Izabela Borek, Benjamin Seeliger, Sascha David, Julius J. Schmidt, Gregor Gorkiewicz, Martin Zacharias, Tobias Welte, Horst Olschewski, Akos Heinemann, Malgorzata Wygrecka, Grazyna Kwapiszewska
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Immunology
Subjects:
extracellular matrix
matrikines
acute lung injury
neutrophils
endothelium
platelets
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188079/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1188079/full

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