First High-Resolution Crystal Structures of DNA:2′-<i>O</i>-Methyl-RNA Heteroduplexes

Heteroduplexes composed of all-DNA and all-2′-OMe RNA strands do not occur in nature, but they have found application in the development of molecular beacons and could also be used as aptamers or elements of nucleic acid-based nanostructures that will contain such structural motifs. The crystallizat...

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Bibliographic Details
Main Authors: Rafał Dolot, Anna Maciaszek, Barbara Mikołajczyk, Barbara Nawrot
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Crystals
Subjects:
Online Access:https://www.mdpi.com/2073-4352/12/6/760