In Vitro – In Vivo Evaluation of Sustained – Release Lithium Carbonate Matrix Tablets: Influence of Hydrophilic Matrix Materials

Background: Conventional Lithium carbonate (LC) tablets produce rapid and relatively high peak blood levels resulting in adverse effects. These drawbacks can be overcome by designing a suitable sustained or controlled-release LC preparation. Methods: Sustained-release matrix tablets were therefore d...

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Bibliographic Details
Main Authors: J Emami, N Tavakoli, A Movahedian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2004-04-01
Series:Journal of Research in Medical Sciences
Online Access:http://journals.mui.ac.ir/jrms/article/view/890