Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis

Testicular exosomes disturb the immunosuppressive phenotype of testicular macrophages mediated by miR-155-5p in uropathogenic Escherichia coli-induced orchitis

Male reproductive infections are known to shape the immunological homeostasis of the testes, leading to male infertility. However, the specific pathogenesis of these changes remains poorly understood. Exosomes released in the inflammatory microenvironment are important in communication between the l...

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Bibliographic Details
Main Authors: Jia Xu, Chao He, Yi-Wei Fang, Zhi-Yong Hu, Mei-Lin Peng, Yuan-Yao Chen, Yu-Fang Su, Chun-Yan Liu, Hui-Ping Zhang, Kai Zhao
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Asian Journal of Andrology
Subjects:
male infertility; mir-155-5p; orchitis; testicular exosome; testicular macrophage polarization
Online Access:http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=3;spage=389;epage=397;aulast=

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http://www.ajandrology.com/article.asp?issn=1008-682X;year=2023;volume=25;issue=3;spage=389;epage=397;aulast=

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