Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma

Fatostatin induces ferroptosis through inhibition of the AKT/mTORC1/GPX4 signaling pathway in glioblastoma

Abstract Glioblastoma multiforme (GBM) is the most common and fatal primary malignant central nervous system tumor in adults. Although there are multiple treatments, the median survival of GBM patients is unsatisfactory, which has prompted us to continuously investigate new therapeutic strategies, i...

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Bibliographic Details
Main Authors: Jiayang Cai, Zhang Ye, Yuanyuan Hu, Liguo Ye, Lun Gao, Yixuan Wang, Qian sun, Shiao Tong, Shenqi Zhang, Liquan Wu, Ji’an Yang, Qianxue Chen
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05738-8

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https://doi.org/10.1038/s41419-023-05738-8

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